SNI: Week 20

The sun close up, with the Brightbeam logo and the words Sector Updates: WK20.

Welcome to all the AI news that matters this week – across tech, biopharma, medtech, advanced manufacturing and insurance. The wins, the fails and the somewhere in-betweens.

tl;dr: The public boos, the money cheers

It’s not been the best of weeks for Irish AI sentiment. Research revealed half of workers (opens in a new tab) are expected to use AI without enough training. And the Irish Times argued women could be the losers (opens in a new tab) in the workplace transition. This was in addition to the 720 Covalen workers taking strike action (opens in a new tab) against AI, while LinkedIn cut 900 jobs (opens in a new tab) – although only 78 are at risk in Ireland – as parent Microsoft restructures around AI. See more on our take here (opens in a new tab).

AI’s public profile also hit a new low as a Gallup poll explained that 70% of Americans oppose (opens in a new tab) new data-centres – making AI less popular than nuclear power.

So it might have been fortunate that Figure AI’s livestreaming of humanoid robots (opens in a new tab) running autonomous warehouse ops didn’t make it into the headlines.

But, of course, the spoken-word commentators were eager to redress the balance. Nathaniel Whittemore on the AI Daily Brief (opens in a new tab) spent 15 minutes explaining how AI will create more jobs than it destroys. He also hypothesised they’ll be one human care-giver per 100-150 patients – scaling to millions of net new jobs globally. And Marc Andreessen was equally upbeat – claiming leading-edge programmers are now 20x more productive (opens in a new tab).

Capital couldn’t have nodded more vigorously. Cerebras priced its IPO at $185 (opens in a new tab), opened at $350 and closed at $311.07 – a 68% first-day pop. More than $5.5bn was raised against a $95bn closing market cap. The largest US tech listing since Uber in 2019.

Almost as significant was Long Lake’s $6.3bn take-private (opens in a new tab) of American Express Global Business Travel – to reinvigorate the business with AI.

Dublin also got a lift from Enterprise Ireland’s €21m National Accelerator (opens in a new tab), as KPMG opened its EU AI Hub (opens in a new tab) – a bet on multi-year EU AI Act compliance work.

On the pharma side, Isomorphic Labs raised $2.1bn in he largest AI drug-discovery raise on record (opens in a new tab). Purely philanthropically, Anthropic and the Gates Foundation formed a $200m AI pact (opens in a new tab) for health and education in low- and middle-income countries.

But it wasn’t all upside for Dario’s crew. Anthropic enraged the developer community (opens in a new tab) with subscription changes. And, in an unrelated decision, Microsoft cancelled its own Claude Code licences (opens in a new tab).

Which made Anthropic’s explanation that the model’s blackmail behaviour traces back (opens in a new tab) to AI-doomer literature seem even bleaker.

So let’s change the mood – with everything else worth reading this week:

AI & tech:

Biopharma:

Medtech:

Advanced manufacturing:

Insurance:

But what set podcast tongues a-wagging?

The token subsidy era is ending.

Nathaniel Whittemore on the AI Daily Brief (opens in a new tab) calls Anthropic’s pricing change the visible end of the AI subsidy era. The six-month window in which a $200 Claude Max plan delivered $2,000-$5,000 of API-equivalent compute is closing for usage outside Anthropic’s own Claude Code harness.

Why? Because compute is now a binding constraint – and Anthropic is choosing to ration subsidy toward enterprise-routed traffic. OpenAI will likely follow.

The chip-cost bargain has broken.

Azeem Azhar on Exponential View (opens in a new tab) argues that Bloomberg’s report of TSMC declining to deploy ASML’s chipmaking tools – on cost grounds – may be the first concrete signal that the economic side of Moore’s Law has reversed.

Cost per transistor stopped falling in 2011; the narrower transistors-per-wafer-dollar measure is now turning too.

But capital is still backing the multiplier play.

Long Lake CEO Alexander Taubman makes the case to No Priors (opens in a new tab) for AI-driven roll-ups of services businesses, using the announced $6.3bn take-private of Amex GBT as the hook. The Long Lake thesis takes the rising compute bill as a given and routes around it: do not run a cost-cutting playbook, give frontline employees AI superpowers, and capture the productivity uplift inside the operating company.

The operational evidence supporting the thesis appears impressive. Long Lake’s HOA management business has moved from a 0-5% growth baseline to 20% annually post-AI, with employee retention rising sharply, customer retention rising, and pay positioned to rise with marginal productivity.

Taubman estimates AI penetration in the services industries on Long Lake’s target list at roughly 1%, and the addressable TAM at over $20tn. Which is something worth thinking about this weekend.

Thank you for reading the latest report. Come back next week for all the AI news you need to know in your sector.

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